i would check you didn't lose spark on one cylinder first, double check your ignition wires and make sure everything is seated.
its not impossible for one ignition wire to vibrate itself out of the cap or one of the plugs.
you can also check timing and see if its still correct. you can also use the timing light to check firing on all 8 cylinders.
i had a petronix ignition where the magnetic ring went bad, and one cylinder was firing when it felt like it.
next i would look at the carb, make sure the accelerator pump is working. verify it squirts when the throttle is moved.
when the engine is running, you can shin a light down the ventures of the carb and increase the throttle and make sure the squirters are working and the ventures are releasing fuel.
before you tear the carb apart, you can also try:
if you check all the wires and check the timing and things still aren't right you could try throwing points on it and see if things change.
try a different coil, and see if the problem remains.
make sure the vacuum advance is working, try pluging off the advance and see if the problem goes away(could be a vaccum leak from the vacuum advance)