The good thing about Holley carbs is they are very tunable, pretty much every component can be changed out or adjusted.
The bad thing about Holley carbs is they are very tunable, you can go crazy changing things out to get them to run 'perfect'.
But don't confuse 'perfect' with 'drivability'. You're not trying to knock a tenth off your 60 foot times. You probably just want a setup that starts easy, idles well, cruises nice, doesn't bog or stumble when you go from a stop to either normal or spirited driving. You're not tracking the car or drag racing every weekend. You probably don't want to spend a lot of money and time chasing those last 10 or so horses or tenths of a second.
So, that being said. You can do a lot with a holley by only adjusting a few things:
1. idle screws (adjust in/out for smooth idle)
2. power valve (get one that works with your engine vacuum range)
3. Jets (proper for your cruise on the primary and power on your secondary , which is why the secondaries are usually a little fatter)
4. Secondary vacuum spring you want one that doesn't bog the engine nor one that you can 'feel it come on')
Also, make sure:
1. The choke is adjusted correctly (not hard to do)
2. Accel pump is adjusted correctly (also not hard to do). Again, most don't need to swap out the cam or cam position
3. Float levels are adjusted
4. That it does open to WOT when the gas pedal is depressed all of the way.
Sure, you can mess with:
1. accel pump size
2. accel pump cams and positions
3. accel shooter sizes, types
4. metering plates
5. types of floats
6. the list goes on and on including crap folks do with a drill or piece of wire
But, in my humble opinion, you don't really need to do any of those things for a street driven car that has a reasonable cam.
So if you decide to dive into tuning your holley watch some videos on how to do it and stick with the basics. You can be pretty successful tuning with a vacuum gauge and a bit more specific with an AFR meter. Or take it to a speed shop with a dyno.
And don't confuse 'easy to tune' with 'easy to change'. Once the carb is set up for your daily driving situation you are done. Being able to swap out things like jets quickly only benefits racers or people that change altitudes a lot.