Factory rods are fine for the 450 power level- hell they are probably fine for 600+ perhaps if you are changing bearings go to the new coated bearings
http://underthehood.mahleclevite.com/?p=169
Balance is something that pays huge dividends. If it was balanced before and you have seen the spec sheet leave it alone, if it was not or they tell you it was without being able to provide numbers-then get the rotating assembly balanced again. Think of your engine as 8 individual engines tied together-you want each to be as exactly made to your spec as possible- vibration is also about harmonics imagine the crankshaft flexing at each bearing like sending a ripple down a rope
whatever cam you Choose verify that the lifters are Cleveland specific
read this link about lubrication
http://www.cartechbooks.com/techtips/351-cleveland-lubrication/
again, it is one man's opinion-but he is very experienced with Cleveland engines and following his advice cost little more than time
I think a great purchase is
http://www.cartechbooks.com/ford-351-cleveland-engines-how-to-build-for-max-performance.html
as it will explain what and why as well as give you lots of alternatives and sources. Just never read such a book after you have built your engine!
Truthfully, I believe the Cleveland stock bottom end suffered from poor rod bolts and cast pistons-those two changes and good clearances will give you a bottom end that will last many years in a 450 horse application. The heads need attention in that the factory intake valves were 2 pieces welded together and they tend to fail and destroy engines. Roller rocker arms and adjustable valvetrain are nice upgrades that reduce friction and free up horsepower-you can try and port heads, but the 4V ports are so large that there is no real point. Some people run port fillers, but below 6000 rpms they won't add any power and they are really not necessary.
You already have a 3.25 rear end and with the multiplication of torque inherent to an automatic transmission, you can keep your engine on its power band one big mistake is thinking a 4V cleveland should cruise at 1500 rpm-it just won't like it in any respect- If all of your driving results in the engine being primarily between 2300 and 6000 rpm, a stock 4V cleveland with just a few upgrades will do it all very nicely
My sister and BIL and nephew are in Toronto and we visit every year or two, driving up from Tennessee wither thru Detroit or Buffalo. Maybe someday I'll get to see your car in person